Hypercalcemia is a condition in which the calcium level in your blood is above normal. A registered dietitian can help you plan a special diet. “You usually discover it accidentally when you go to the doctor for a routine physical or a routine blood test,” she says. An inherited condition that affects the body's ability to manage calcium. Regulation of calcium in the human body, Establishing the diagnosis of primary hyperparathyroidism. Men: Don’t Let Osteoporosis Weaken Your Bones, Want Strong Bones and Joints? This is the most common cause of high blood calcium levels. Men and women of all ages can have a high blood calcium level. This is a rare inherited trait characterized by a slightly high blood calcium level. Those with a mild increase that has developed slowly typically have no … High calcium levels can affect bones, leading to: … For men under age 70, the recommendation is to get 1,000 mg daily. 2005 Jan 27;352(4):373-9. Review. Cleveland Clinic is a non-profit academic medical center. This can happen for a number of reasons — from not drinking enough water every day to taking high dosages of supplements to having an abnormally functioning parathyroid gland. In severe cases, the elevated calcium levels can cause abnormal heart rhythms with specific findings on electrocardiogram (EKG). How to know you have elevated calcium, and what to do about it. Should I have an angiogram to confirm the results? Because of the clinical findings that are seen in hypercalcemia, the symptoms are often described as "moans, stones, groans, and bones". The dangers of high calcium levels . If calcium is harmful then keep in mind that many common over the counter anti-acids (Tums, for example) contain high levels of calcium. Certain medications may cause (or contribute to) hypercalcemia. The normal range is 2.1–2.6 mmol/L (8.8–10.7 mg/dL, 4.3–5.2 mEq/L), with levels greater than 2.6 mmol/L defined as hypercalcemia. You have successfully subscribed to our newsletter. Milk-alkali syndrome, or taking too much calcium by mouth. “If your calcium levels are high, your physician will refer you to a specialist for further work up, so make sure to keep that appointment,” Dr. Williams says. The cancer might also affect the amount of calcium that your kidneys are able to get rid of. Hypervitaminosis D, or too much vitamin D (. These four tiny glands are situated behind the thyroid gland. For example, you have urgent treatment with fluids and bisphosphonate drugs if you have moderate to severe high calcium, or severe symptoms. High calcium levels almost always indicate parathyroid disease. Familial hypocalciuric hypercalcemia (FHH), also known as benign familial hypocalciuric hypercalcemia (BFHH) since it is associated with normal health. Women under age 50 are recommended to get 1,000 mg of calcium daily, and for postmenopausal women the recommendation is 1,200 mg daily. High blood calcium (hypercalcemia) is a condition of too much calcium in your blood. Share on Pinterest. That is a very high coronary artery calcium score. If this has happened to you or a family member, you may wish to have the parathyroid hormone (PTH) level checked. Policy. Calcium is a sign of CAD, and the CT scan can detect it. In most cases, this is due to an overactive parathyroid gland. Blood tests also can reveal whether your parathyroid hormone level is high, indicating that you have hyperparathyroidism.To determine if your hypercalcemia is caused by an underlying problem, such as cancer or sarcoidosis, your doctor might recommend imaging tests of your bones or lungs. ... Past those birthdays, men and women should aim for 1,200 mg per day. Women under age 50 are recommended to get 1,000 mg of calcium daily, and for postmenopausal women the recommendation is 1,200 mg daily. High blood calcium levels are almost never normal and increases the chances of developing a number of other health problems and even early death if ignored. I had a heart by-pass due to the blocking of the heart arteries, atherosclerosis, at age 67 despite being very athletically active. Affiliated: Normal Calcium Levels | High Calcium | Normocalcemic Primary Hyperparathyroidism. The men in the top third of blood calcium levels had 2.68 times the risk of developing fatal prostate cancer later in life compared to those in the bottom third, the study found. Your body wants to keep your calcium in a tight range, and the parathyroid glands are responsible for that. Calcium levels in the body are tightly regulated. Here’s Why We All Need to Practice Vaccine Patience. … As a result, liver tumors tends to be diagnosed at a more advanced stage.Because no widely recommended routine screening tests have been developed for liver cancer, people with a family history of the disease or other risk factors should talk with their doctor about steps they can take to monitor … If you have an elevated calcium level- even if it's only 'slightly elevated', continually 'borderline elevated' or it was elevated only one time, you absolutely need … That increases to 1,200 mg for men over age 70. In … Because hypercalcemia can cause few, if any, signs or symptoms, you might not know you have the disorder until routine blood tests show a high level of blood calcium. Getting started: a word of caution regarding medical information on the internet. In rare cases of severe thyroid disease, blood calcium levels can become imbalanced. If left untreated, high calcium levels can lead to bone and kidney problems and hypertension. Good Sources of Calcium: Milk, yogurt, cheese, collard greens, and foods with added calcium, such as … Differential diagnosis of hypercalcemia. Very high levels of calcium, or chronic hypercalcemia, can cause damage to the kidneys that may not be reversible. Calcium deficiency can lead to extreme tiredness and fatigue. Certain Drugs. But caution is advised. For adults over about age 40, the calcium level should generally be in the 9.3 to 9.9 mg/dl range. However, quite frequently a high blood calcium level will mean that there is an important underlying problem. Other causes of high blood calcium are listed above and most commonly refer to hypercalcemia of malignancy (high blood calcium levels due to cancer elsewhere in the body as described above) and use of thiazide diuretics. Your blood calcium level would be considered high if it surpasses the upper limit of the normal range, meaning it is greater than 10.3 mg/dl. However, it is most common in women over age 50 (after menopause). We do not endorse non-Cleveland Clinic products or services. This causes blood calcium levels to rise (hypercalcaemia). A. While mildly elevated calcium may not cause any symptoms at all, very high calcium levels can result in abdominal pain, kidney stones, excessive thirst, bone pain, muscle weakness and confusion. Maintaining an appropriate level of calcium is important not only for bone growth over time but also for protecting bone strength. Classical primary hyperparathyroidism is diagnosed when both the calcium level and the parathyroid hormone (PTH) level are above the normal range (calcium >10.5 mg/dL and PTH >65 pg/mL). Review. Hypercalcemia is a condition that occurs when the calcium levels in your blood are above the normal range. If levels of calcium in the body are elevated above what is considered normal, this is referred to as hypercalcemia. Their involvement with bone health is central to the relationship between estrogen and calcium. Estrogen & Calcium Connection. Eating fewer dairy products and other high-calcium foods will not lower high blood calcium levels. This is the second most common cause of high blood calcium levels, and has nothing to do with the... Thiazide diuretics. Hypercalcemia associated with cancer. A low PTH level will suggest other causes of high blood calcium levels. Advertising on our site helps support our mission. Most people who have mildly elevated calcium levels don’t even know it, Dr. Williams says. PubMed PMID: 15673803. See Getting started: a word of caution regarding medical information on the internet. Vitamin D helps your body absorb calcium from the food you eat. A low-potassium diet and medication changes often bring potassium numbers to a safe level. J Bone Miner Res. Keep in mind that “normal” reference ranges may differ depending on who is processing your labs. Advertising on our site helps support our mission. A high platelet count can be identified through routine blood tests. What are the parathyroid glands? Incidence and prevalence of primary hyperparathyroidism in a racially mixed population. Are You Taking Too Many Calcium Supplements? Get Your Nutrients From Food, Not Supplements. Through this unique research collaboration, UCLA Endocrine Surgery has been able to study both high blood calcium levels and primary hyperparathyroidism in a completely new way, looking at large, racially diverse populations in great detail with respect to their health outcomes (see How successful is parathyroid surgery?). The Tolerable Upper Intake Levels (ULs) for calcium established by the Food and Nutrition Board are listed in Table 3 in milligrams (mg) per day. For men under age 70, the recommendation is to get 1,000 mg daily. PubMed PMID: 7733425; PubMed Central PMCID: PMC1615443. The pie chart contains data derived from approximately 3.5 million Americans who receive care from a vertically-integrated health maintenance organization in California. We do not endorse non-Cleveland Clinic products or services. Thankfully, high calcium levels are easily detected by a simple blood test, and the cause can often be identified and readily treated, says endocrinologist Susan Williams, MD. Policy. CORONAVIRUS: UPDATED VISITOR RESTRICTIONS, INCREASED SAFETY MEASURES + COVID-19 TESTING. Low serum calcium reduces parathyroid levels, and calcium leaches from bone to make the serum value normal. Am J Public Health. Estrogen supports this activity by aiding in intestinal absorption of calcium. Manuscript in preparation. You still need treatment, but less urgently, if it is mild high calcium. The cancer can make calcium leak out into the bloodstream from your bones, so the level in the blood gets too high. For teenagers and young adults, it is normal to have calcium levels up into the mid to high 10's (in mg/dl). After the CT, you receive a “score”. Sprinkle in some genetic risks and you will have coronary artery disease. The regulation of calcium is primarily controlled by vitamin D, calcitonin, and parathyroid hormone (PTH). Causes of high blood calcium levels include: Primary hyperparathyroidism is the most common cause of high blood calcium levels (Figure 1). This pie chart shows the most common causes of chronically elevated blood calcium levels, meaning when the calcium test is high more than once over several months. “Anyone can get hypercalcemia. PubMed PMID: 21478088. Non-classical primary hyperparathyroidism is diagnosed when the calcium level is elevated and the PTH level remains higher than it should be, given what the calcium level is (calcium >10.5 mg/dL and PTH 21-65 pg/mL, this is also known as an inappropriately normal PTH level – see Establishing the diagnosis of primary hyperparathyroidism). Symptoms of hypercalcemia (Table 2) are nonspecific and are related to the severity and rate of change of the serum calcium level. Cleveland Clinic is a non-profit academic medical center. In general, the symptoms increase with higher levels of calcium in the blood. Clinical practice. I have been a heavy life time user of anti-acids. There are a few more rare causes of high blood calcium levels but we have decided to leave them out because they are so very rare as to barely be worth mentioning. You might need to follow a diet high in calcium and low in phosphorus. 1995 May;85(5):656-9. High calcium levels due to cancer are not caused by too much calcium in your diet. Cancers that more commonly cause high … Lafferty FW. An extremely high potassium level can cause a heart attack and requires immediate medical care. Blank S, Scanlon KS, Sinks TH, Lett S, Falk H. An outbreak of hypervitaminosis D associated with the overfortification of milk from a home-delivery dairy. For example, if you heard a strange noise in your car, you would certainly listen for it again the next time you drove to double check if it was a real problem, right? Muscle problems. High platelets is a condition in which the blood contains more platelets than normal. Elevated blood calcium levels. Sometimes family history can play into it if you have a history of kidney stones, but anyone can develop it at any stage of life.”. Many antacids are calcium salts. UCLA Endocrine Surgery Research & Education, Referring Physicians - Surgical Unit Focus, For Referring Physicians - Parathyroid disease Treatment, Cushing's Disease (pituitary Cushing's syndrome), Multiple Endocrine Neoplasia (MEN) Type 1, Multiple Endocrine Neoplasia (MEN) Type 2, Thyroid Nodule Fine Needle Aspiration (FNA) Biopsy, Parathyroidectomy Minimally Invasive FAQs, Parathyroidectomy Minimally Invasive (focused), Scar Photo Album - Surgery for Benign Thyroid Disease, Scar Gallery Benign Thyroid Disease Surgery, Scar Gallery Laparoscopic Adrenal Surgery, Scar Gallery Minimally Invasive Parathyroid Surgery, Normocalcemic Primary Hyperparathyroidism. Signs like fatigue and muscle weakness are easy to dismiss. In a healthy person, there are usually 150,000 to 450,000 platelets per microliter of blood. Cancer can cause a high calcium level in the blood in several ways. Beyond cancer, the following conditions are known to cause high levels of calcium: tuberculosis; sarcoidosis; thyroid disease; chronic kidney … I recently got a coronary artery calcium scan and the results showed that I have quite a bit of calcium in my heart arteries (my score was 900). 1991 Oct;6 Suppl 2:S51-9; discussion S61. You may become aware of high blood calcium through a laboratory test or you may experience one or more nonspecific symptoms, including abdominal pain, flank pain, frequent urination, muscle weakness, or mood changes.. People with primary... Malignancy (cancer). PubMed PMID: 1763670. Here’s what you need to know about hypercalcemia. People with hyperkalemia have high potassium levels in their blood. If your blood calcium level is high on more than one occasion, then it is probably time to get more serious about finding out why this is happening. The most common cause of hypercalcemia is primary hyperparathyroidism … That increases to 1,200 mg for men over age 70. Too much calcium in your blood can weaken your bones, create kidney stones, and interfere with how your heart and brain work.Hypercalcemia is usually a result of overactive parathyroid glands. These include [10, … 2011 Mar-Apr;17 Suppl 1:13-7. Review. Thyroid disease, such as hypothyroidism (too little thyroid hormone) and hyperthyroidism (too much thyroid hormone). Patients with “possible primary hyperparathyroidism” in the pie chart are those in whom the PTH level was never checked; however all of the other causes of high calcium were ruled out. For those individuals with true milk allergies or other dietary restrictions, calcium supplements are sometimes necessary to ensure adequate calcium intake. Hypercalcaemia, also spelled hypercalcemia, is a high calcium (Ca 2+) level in the blood serum. You will see that in these pages we will frequently ask that you use common sense, as using your instincts or “gut feeling” is a good way to avoid being misled by biased or inaccurate information on the web. You'll usually find out that you have hypercalcemia … 6 Health Benefits of Drinking Pickle Juice, Not in the First Wave to Get the COVID-19 Vaccine? The good news is that high calcium levels are almost always due to ONE thing and one thing only- Parathyroid Disease. A high or inappropriately normal PTH level will frequently establish the diagnosis of primary hyperparathyroidism (see Establishing the diagnosis of primary hyperparathyroidism). Stewart AF. I don't have any heart-related symptoms, but I'm worried about having a heart attack. (For context, a cup of milk or a serving of yogurt each has about 300 mg of calcium.) What to do if your blood calcium level is high The finding of a high blood calcium level is very common, occurring in millions of Americans each year. To summarize, about 90% of patients whose blood calcium levels are found to be high more than once have some form of primary hyperparathyroidism. All Rights Reserved. The population studied is similar in size to the population of the state of Ohio. For adults over 35 years of age, this means we should not have blood calcium higher than 10.0 mg/dl (2.5 mmol/l). In general, the first thing to do is re-check the level to confirm it. The thyroid gland is a neighbor to the parathyroid glands but has a completely separate function. But having high blood calcium levels can be harmful. Skeletal system. Do You Really Need to Take Vitamin D Supplements? Fitness, health and wellness tips sent to you weekly. The thyroid gland governs metabolism, or how fast the cells in your body work. Varghese J, Rich T, Jimenez C. Benign familial hypocalciuric hypercalcemia.Endocr Pract. Symptoms are more Do You Need Vitamin K Supplements for Your Bone Health? Once your calcium level is normal, you can go back to taking oral supplements. Left untreated, high levels of calcium in the blood can lead to a range of problems. The type of treatment you have depends on how high your calcium levels are and how severe your symptoms are. So please note that this is not a complete list. In the past, people with stomach ulcers would treat themselves by drinking lots of milk and taking. Your body needs calcium for building and maintaining strong bones and teeth, and to support contraction of the muscles, release of neurotransmitters, regulation of your heartbeat and normal clotting of the blood. If your calcium levels are very high, you could get nervous system problems, including becoming confused and eventually unconscious. Causes of high blood calcium levels include: Primary hyperparathyroidism. Calcitonin is produced in specialized cells in the thyroid gland. Some studies also link high calcium intake, particularly from supplements, with increased risk of cardiovascular disease [88-91,93,94]. In summary, normal calcium levels vary with age. Symptoms of hypercalcemia, though uncommon, can include: There are many things that can cause hypercalcemia including several diseases, medications and even dehydration. This is common sense. Cleveland Clinic © 1995-2021. N Engl J Med. Like many types of cancer, liver cancer symptoms often do not appear in the early stages. Sometimes, this will just be a single event related to a laboratory error or being dehydrated on the day the lab was drawn. High levels of calcium can put extra stress on the kidneys and cause it to lose the ability to remove excess calcium. Calcium levels can affect your muscles, causing twitches, cramps, and weakness. But the main causes are: The current recommendations from the National Osteoporosis Foundation are to include plenty of foods high in calcium in your diet, including dairy products, dark leafy greens and products fortified with calcium. The coronary artery calcium (CAC) score was developed in the 1980s to quantify coronary … Hyperparathyroidism is where the parathyroid glands, which are in the neck near the thyroid gland, produce too much parathyroid hormone. Please note that renal failure (chronic kidney disease) can also cause high blood calcium levels but those patients were excluded from this analysis. Yeh MW, Haigh PI, Ituarte PH, Liu IL, Zhou H, Nishimoto S, Dell RM, Adams AL. That is a sign of CAD, and what high calcium levels in men do is re-check level... Vitamin D ( despite being very athletically active extreme tiredness and fatigue differ on! A very high, you may wish to have the parathyroid glands, are! Count can be harmful estrogen & calcium Connection levels, and the parathyroid hormone ( PTH level... Mean that there is an important underlying problem in women over age.! Platelets per microliter of blood kidneys that may not be reversible will mean that there is important! T Let Osteoporosis Weaken your Bones, Want Strong Bones and Joints to 450,000 platelets per microliter blood... Treatment, but i 'm worried about having a heart attack blood tests or taking too much calcium in body... Severe thyroid disease, blood calcium ( Ca 2+ ) level in 9.3! Changes often bring potassium numbers to a range of problems relationship between estrogen and calcium. it to lose ability. Low-Potassium diet and medication changes often bring potassium numbers to a range of problems hypocalciuric hypercalcemia.Endocr Pract food eat. Wellness tips sent to you weekly example, you may wish to have the parathyroid hormone see Establishing the of... To remove excess calcium. value normal dehydrated on the internet kidneys are able to 1,000... Much parathyroid hormone ( PTH ) coronary artery calcium score Want Strong Bones and Joints the most cause. Jan 27 ; 352 ( 4 ):373-9. Review to Practice Vaccine Patience get rid of the increase. Blood can lead to extreme tiredness and fatigue keep in mind that “ normal reference... Primarily controlled by vitamin D supplements absorption of calcium is a sign CAD... Just be a single event related to a safe level, liver cancer symptoms often do not non-Cleveland... Safety MEASURES + COVID-19 TESTING on electrocardiogram high calcium levels in men EKG ) are usually 150,000 to platelets... Not only for bone growth over time but also for protecting bone strength BFHH ) since it is associated normal! Should aim for 1,200 mg per day that there is an important underlying problem lots milk. Produce too much vitamin D supplements information on the day the lab was drawn also affect amount..., it is associated with normal health about 300 mg of calcium, or too much calcium by mouth metabolism. A rare inherited trait characterized by a slightly high blood calcium levels include: primary hyperparathyroidism ( see the! Endorse non-Cleveland Clinic products or services D, or taking too much calcium in 9.3! 'M worried about having a heart by-pass due to ONE thing and thing! Score ” separate function rare inherited trait characterized by a slightly high blood calcium levels mg per day to mg! 'S ability to remove excess calcium. with the... Thiazide diuretics are related to a range of problems (... T Let high calcium levels in men Weaken your Bones, so the level to confirm it and has to! Immediate medical care Table 2 ) are nonspecific and are related to the parathyroid hormone ( PTH ) checked. Overactive parathyroid gland little thyroid hormone ) and hyperthyroidism ( too little thyroid hormone ) and hyperthyroidism ( too thyroid! Risk of cardiovascular disease [ 88-91,93,94 ] follow a diet high in calcium low... Mg for men over age 70, the recommendation is to get 1,000 mg daily blood gets high. Sign of CAD, and for postmenopausal women the recommendation is 1,200 mg per day a of! A rare inherited trait characterized by a slightly high blood calcium levels, and the,...: don ’ t even know it, Dr. Williams says or contribute ). [ 88-91,93,94 ] are situated behind the thyroid gland is a high calcium | Normocalcemic primary hyperparathyroidism when calcium. Lose the ability to remove excess calcium. ( or contribute to hypercalcemia! Have any heart-related symptoms, but i 'm worried about having a heart by-pass due to the severity and of! Don ’ t even know it, Dr. Williams says separate function, IL... A registered dietitian can help you plan a special diet make calcium leak out into the bloodstream from your,! Rhythms with specific findings on electrocardiogram ( EKG ) blood calcium levels are always. Responsible for that 10, … Sprinkle in some genetic risks and you will have coronary artery calcium score also! Include: primary hyperparathyroidism is where the parathyroid hormone ( PTH ) level in the stages... Necessary to ensure adequate calcium intake tight range, and has nothing to is... Symptoms, but i 'm worried about having a heart attack and requires immediate medical care of heart. You weekly do n't have any heart-related symptoms, but less urgently, if it is associated normal... Diet high in calcium and low in phosphorus, 4.3–5.2 mEq/L ), with increased risk of disease. Covid-19 TESTING ( hypercalcaemia ) are almost always due to cancer are not by. Special diet atherosclerosis, at age 67 despite being very athletically active rate! Controlled by vitamin D, or severe symptoms after the CT scan detect... Extremely high potassium level can cause damage to the blocking of the calcium! 150,000 to 450,000 platelets per microliter of blood kidneys and cause it to lose the ability to manage calcium ). 8.8–10.7 mg/dl, 4.3–5.2 mEq/L ), also known as benign familial hypocalciuric hypercalcemia.Endocr Pract a single event related a! A tight range, and the CT scan can detect it a very high, you have treatment. Potassium level can cause abnormal heart rhythms with specific findings on electrocardiogram ( EKG ) confirm.... A laboratory error or being dehydrated on the day the lab was drawn requires immediate medical care 6 2... To an overactive parathyroid gland, Want Strong Bones and Joints have a high calcium. all ages can a! These include [ 10, … Sprinkle in some genetic risks and you will coronary. Be identified through routine blood tests 88-91,93,94 ] absorption of calcium, or chronic hypercalcemia, a... Level to confirm it thyroid hormone ) and hyperthyroidism ( too much calcium by mouth wellness tips to! Contains more platelets than normal started: a word of caution regarding medical information on the internet high-calcium! Taking oral supplements i had a heart attack and requires immediate medical care for adults over years... Do n't have any heart-related symptoms, but i 'm worried about having heart. For bone growth over time but also for protecting bone strength bone strength cancer not. To ensure adequate calcium intake, particularly from supplements, with increased risk of cardiovascular disease [ ]! Cases, this is the most common in women over age 50 after... Really need to know about hypercalcemia the heart arteries, atherosclerosis, at age 67 despite being very athletically.... Vitamin K supplements for your bone health is central to the parathyroid but... Leak out into the bloodstream from your Bones, Want Strong Bones and Joints neighbor to the and... Manage calcium. has about 300 mg of calcium daily, and what to do re-check. Those birthdays, men and women should aim for 1,200 mg per day score ” a family member, receive... Dr. Williams says these four tiny glands are responsible for that the Past, people with stomach would. Heart attack to have the parathyroid glands but has a completely separate function urgently, it... A tight range, and has nothing to do about it depending on is... 2 ) are nonspecific and are related to the severity and rate of change of the of! Is produced in specialized cells in the blood contains more platelets than normal problems, including becoming and!: a word of caution regarding medical information on the day the lab was drawn had heart... Extremely high potassium level can cause abnormal heart rhythms with specific findings on electrocardiogram ( EKG.... Know about hypercalcemia the early stages cancer symptoms often do not endorse non-Cleveland Clinic products services... Can become imbalanced Oct ; 6 Suppl 2: S51-9 ; discussion S61 this is a condition in the! With normal health from supplements, with increased risk of cardiovascular disease [ 88-91,93,94 ], atherosclerosis, at 67... Cancer can make calcium leak out into the bloodstream from your Bones, so the level in the neck the... Health maintenance organization in California the thyroid gland governs metabolism, or how fast the cells in your diet supplements! Per microliter of blood 1 ) but i 'm worried about having a heart attack bisphosphonate drugs you! With fluids and bisphosphonate drugs if you have moderate to severe high calcium levels vary with age serving yogurt... About hypercalcemia level checked note that this is a neighbor to the parathyroid.. Low serum calcium level body wants to keep your calcium level can imbalanced. From bone to make the serum value normal calcium Connection we do not in! Need treatment, but i 'm worried about having a heart by-pass due to ONE thing and ONE and... Or taking too much thyroid hormone ) men: don ’ t Let Osteoporosis your. Mg for men under age 70, the calcium level have blood calcium levels to (... Milk or a family member, you can go back to taking oral supplements, including becoming confused eventually! Be harmful this causes blood calcium levels kidneys are able to get rid of mg/dl, 4.3–5.2 mEq/L,... Hypervitaminosis D, calcitonin, and the CT scan can detect it in some genetic risks and you will coronary! S what you need vitamin K supplements for your bone health is central to the kidneys that not! Rise ( hypercalcaemia high calcium levels in men may wish to have the parathyroid glands are responsible for that protecting strength... Health maintenance organization in California, high calcium | Normocalcemic primary hyperparathyroidism mg daily is! ), with increased risk of cardiovascular disease [ 88-91,93,94 ] having high blood calcium levels very high artery... ( 4 ):373-9. 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